%0 Journal Article
%T Mathematical Modeling of the Process for Microbial Production of Branched Chained Amino Acids
%A Georgiev T.
%A Todorov K.
%A Ratkov A.
%J Bioautomation
%D 2009
%I 
%X This article deals with modelling of branched chained amino acids production. One of important branched chained amino acid is L-valine. The aim of the article is synthesis of dynamic unstructured model of fed-batch fermentation process with intensive droppings for L-valine production. The presented approach of the investigation includes the following main procedures: description of the process by generalized stoichiometric equations; preliminary data processing and calculation of specific rates for main kinetic variables; identification of the specific rates takes into account the dissolved oxygen tension; establishment and optimisation of dynamic model of the process; simulation researches. MATLAB is used as a research environment.
%K Modelling
%K Optimisation
%K Branched chained amino acids
%K Fed-batch process with droppings
%K L-Valine
%U http://www.clbme.bas.bg/bioautomation/2009/vol_13.4/files/13.4_4.04.pdf