%0 Journal Article
%T Modelling of L-valine Repeated Fed-batch Fermentation Process Taking into Account the Dissolved Oxygen Tension
%A Kalin Todorov
%A Tzanko Georgiev
%A Ignat Dimov
%A Julia Kristeva
%J Bioautomation
%D 2009
%I 
%X This article deals with synthesis of dynamic unstructured model of variable volume fed-batch fermentation process with intensive droppings for L-valine production. The presented approach of the investigation includes the following main procedures: description of the process by generalized stoichiometric equations; preliminary data processing and calculation of specific rates for main kinetic variables; identification of the specific rates takes into account the dissolved oxygen tension; establishment and optimisation of dynamic model of the process; simulation researches. MATLAB is used as a research environment.
%K Modelling
%K Optimisation
%K Repeated fed-batch process
%K Fed-batch process with droppings
%K L-valine.
%U http://www.clbme.bas.bg/bioautomation/2009/vol_12.1/files/12_1.4.pdf