%0 Journal Article
%T Synthesis of Capsaicin Glycosides and 8-Nordihydrocapsaicin Glycosides as Potential Weight-Loss Formulations
%A Hisashi Katsuragi
%A Kei Shimoda
%A Eriko Kimura
%A Hiroki Hamada
%J Biochemistry Insights
%D 2010
%I 
%X The enzymatic synthesis of capsaicin glycosides and 8-nordihydrocapsaicin glycosides was investigated using almond ¦Â-glucosidase and cyclodextrin glucanotransferase (CGTase). Capsaicin and 8-nordihydrocapsaicin were converted into their ¦Â-glucoside and ¦Â-maltooligosaccharide (amylose conjugate), i.e. ¦Â-maltoside and ¦Â-maltotrioside, by sequencial glycosylation with almond ¦Â-glucosidase and CGTase. The ¦Â-glucoside and ¦Â-maltoside of capsaicin and ¦Â-glucoside of 8-nordihydrocapsaicin showed inhibitory effects on high-fat-diet-induced elevations in body weight of mice.
%U http://la-press.com/synthesis-of-capsaicin-glycosides-and-8-nordihydrocapsaicin-glycosides-a1935