%0 Journal Article
%T Fatores associados ¨¤ transfus o de concentrado de hem¨¢cias em prematuros de uma unidade de terapia intensiva Factors associated with packed red blood cell transfusions in premature infants in an intensive care unit
%A Brunnella Alcantara Chagas de Freitas
%A Sylvia do Carmo Castro Franceschini
%J Revista Brasileira de Terapia Intensiva
%D 2012
%I Associa??o de Medicina Intensiva Brasileira
%R 10.1590/s0103-507x2012000300004
%X OBJETIVO: Analisar os fatores associados ¨¤ necessidade de transfus es de concentrados de hem¨¢cias em prematuros de uma unidade de terapia intensiva neonatal. M¨¦TODOS: Estudo transversal de dados secund¨¢rios de prematuros admitidos em unidade de terapia intensiva neonatal entre 2008 e 2010. Foram inclu¨ªdos prematuros com baixo peso ao nascimento. A transfus o de concentrado de hem¨¢cias foi considerada a vari¨¢vel dependente. Empregaram-se os testes do qui-quadrado de Pearson ou exato de Fisher, e calcularam-se as medianas e os valores m¨ªnimos e m¨¢ximos. Calcularam-se raz es de preval¨ºncias pela regress o de Poisson e o coeficiente de correla  o de Pearson. Realizaram-se an¨¢lises de regress o linear. Considerou-se significante p<0,05. RESULTADOS: Estudaram-se 254 prematuros e 39,4% receberam concentrado de hem¨¢cias. As transfus es foram 70% menos prevalentes entre os prematuros com idades gestacionais >32 semanas e 191% mais prevalentes naqueles acometidos por sepse neonatal tardia. O n¨²mero de transfus es por paciente apresentou correla  o negativa com a idade gestacional e positiva com a sepse neonatal tardia. A idade gestacional <32 semanas e a sepse neonatal tardia explicaram 45% das transfus es realizadas (p<0,0001). CONCLUS ES: Os prematuros com idade gestacional <32 semanas e os que evolu¨ªram com sepse neonatal tardia apresentaram maior necessidade de transfus es de concentrados de hem¨¢cias. OBJECTIVE: This study analyzed the factors that are associated with the need for packed red blood cell transfusions in premature infants in a neonatal intensive care unit. METHODS: This study is a cross-sectional study of secondary data from premature infants who were admitted to a neonatal intensive care unit between 2008 and 2010. Premature infants with low birth weight were included. Packed red blood cell transfusion was the dependent variable. Pearson's Chi-square or Fisher's exact tests were used for data analysis, and the median, minimum, and maximum values were calculated. Prevalence ratios were calculated using the Poisson regression and Pearson correlation coefficient. Linear regression analyses were performed. P < 0.05 was considered to be significant. RESULTS: We examined 254 premature infants, and 39.4% of this sample received packed red blood cells. Transfusions were 70% less prevalent in premature infants who were born at >32 weeks of gestation, and 191% more prevalent in infants who exhibited late-onset neonatal sepsis. The number of transfusions per patient was negatively correlated with gestational age and positively correlated with late-onset n
%K Prematuro
%K Transfus o de eritr¨®citos
%K Terapia intensiva neonatal
%K Sepse
%K Infant
%K premature
%K Erythrocyte transfusion
%K Intensive care
%K neonatal
%K Sepsis
%U http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-507X2012000300004