%0 Journal Article
%T Local Therapy of Gonarthrosis Using Autologous Platelet-enriched Plasma
%A L.Yu. Shirokova
%A S.M. Noskov
%A §´.I. Bakhtiarova
%A §¡.V. Snigiryova
%J Sovremennye Tehnologii v Medicine
%D 2012
%I Nizhny Novgorod State Medical Academy of the Ministry of Health and Social Development
%X The aim of the investigation is to assess clinical effect of local (intra-articular) application of autologous platelet-enriched plasma (PEP) in treating gonarthrosis. Materials and methods. Clinical observation of 83 women with gonarthrosis was performed within 3 months. Within 3 weeks the patients were receiving PEP intra-articular injections of 5 ml twice a week. Results. In intra-articular PEP administration in patients with gonarthrosis, the change of knee joint functional state occurs depending on the severity of osteoarthrosis, the most significant change ¡ª in the early stage and almost absent change in severe diseases (complicated by synovitis). In typical gonarthrosis of II¨CIII radiological stages, the positive effect is short-term and observed in early one-month observation period.
%K Gonarthrosis
%K Local therapy
%K Platelet-enriched plasma
%K Osteoarthrosis
%U http://www.stm-journal.ru/_resources/item/669/fields/File/stm-1-2012_s17_p97-100_2.pdf