%0 Journal Article
%T Cost-effectiveness of laser Doppler imaging in burn care in the Netherlands
%A M Jenda Hop
%A Jakob Hiddingh
%A Carlijn Stekelenburg
%A Hester C Kuipers
%A Esther Middelkoop
%A Marianne K Nieuwenhuis
%A Suzanne Polinder
%A Margriet E van Baar
%A the LDI study group
%J BMC Surgery
%D 2013
%I BioMed Central
%R 10.1186/1471-2482-13-2
%X Laser Doppler imaging (LDI) is a technique with which a more accurate (>95%) estimate of burn depth can be made by measuring the dermal perfusion. The actual effect on therapeutic decisions, clinical outcomes and the costs of the introduction of this device, however, are unknown. Before we decide to implement LDI in Dutch burn care, a study on the effectiveness and cost-effectiveness of LDI is necessary.A multicenter randomised controlled trial will be conducted in the Dutch burn centres: Beverwijk, Groningen and Rotterdam. All patients treated as outpatient or admitted to a burn centre within 5 days post burn, with burns of indeterminate depth (burns not obviously superficial or full thickness) and a total body surface area burned of ¡Ü 20% are eligible. A total of 200 patients will be included. Burn depth will be diagnosed by both clinical assessment and laser Doppler imaging between 2¨C5 days post burn in all patients. Subsequently, patients are randomly divided in two groups: ¡®new diagnostic strategy¡¯ versus ¡®current diagnostic strategy¡¯. The results of the LDI-scan will only be provided to the treating clinician in the ¡®new diagnostic strategy¡¯ group. The main endpoint is the effect of LDI on wound healing time.In addition we measure: a) the effect of LDI on other patient outcomes (quality of life, scar quality), b) the effect of LDI on diagnostic and therapeutic decisions, and c) the effect of LDI on total (medical and non-medical) costs and cost-effectiveness.This trial will contribute to our current knowledge on the use of LDI in burn care and will provide evidence on its cost-effectiveness.NCT01489540In patients with burns an early accurate diagnosis of burn depth is essential to determine the most appropriate treatment. Monstrey et al. recently reviewed all current modalities to diagnose burn depth. Bedside clinical examination is the most widely used and least expensive method for burn depth assessment. This technique is effective when diagnosing burns at t
%K Laser doppler imaging
%K Burns
%K Diagnosis
%K Cost-effectiveness analysis
%U http://www.biomedcentral.com/1471-2482/13/2