%0 Journal Article
%T NNAT and DIRAS3 genes are paternally expressed in pigs
%A Cheng Huan-Chen
%A Zhang Feng-Wei
%A Deng Chang-Yan
%A Jiang Cao-De
%J Genetics Selection Evolution
%D 2007
%I BioMed Central
%R 10.1186/1297-9686-39-5-599
%X Although expression and epigenetic differences of imprinted genes have been extensively characterised in man and the mouse, little is known on livestock species. In this study, the polymorphism-based approach was used to detect the imprinting status of NNAT and DIRAS3 genes in five heterozygous pigs (based on SNP) of Large White and Meishan F1 hybrids. The results show that both genes were paternally expressed in all the tested tissues (heart, liver, spleen, lung, kidney, stomach, small intestine, skeletal muscle, fat, uterus, ovary and pituitary). In addition, the NNAT gene had two transcripts in all tested tissues, which is consistent with its counterpart in man and cattle.
%K pig
%K NNAT
%K DIRAS3
%K imprinting
%K paternally expressed
%U http://www.gse-journal.org/content/39/5/599