%0 Journal Article %T On a Seminal Paper by Karlin and McGregor %A Mirta M. Castro %A F. Alberto Grščnbaum %J Symmetry, Integrability and Geometry : Methods and Applications %D 2013 %I National Academy of Science of Ukraine %X The use of spectral methods to study birth-and-death processes was pioneered by S. Karlin and J. McGregor. Their expression for the transition probabilities was made explicit by them in a few cases. Here we complete their analysis and indicate a few applications of their very powerful method. %K birth-and-death processes %K spectral measure %U http://dx.doi.org/10.3842/SIGMA.2013.020