%0 Journal Article %T Changing Epidemiology of HIV in Mumbai: an Application of the Asian Epidemic Model %A Ram Manohar Mishra %A Madhulika Dube %A Damodar Sahu %A Niranjan Saggurti %J Global Journal of Health Science %D 2012 %I %R 10.5539/gjhs.v4n5p100 %X Background: Mumbai is one of the most populous and high HIV prevalence cities in India. It has witnessed substantial changes in HIV-risk behaviors and a decline in HIV prevalence among high-risk groups during the past decade. Aim: To examine the changing pattern in the number of new HIV infections by transmission routes in Mumbai during 2000-2017. Methods: We used the Asian Epidemic Model by dividing the adult population (aged 15 and above) into seven subgroups: brothel-based and non-brothel based female sex workers (FSWs), heterosexual clients of FSWs, men who have sex with men/transgendered people (MSM), injecting drug users (IDUs), general women and general men. The MSM subgroup included homosexual and bisexual men. Results: New HIV infections among adults reduced by 86% during 2000-2010. The highest decline was among FSWs and their heterosexual clients (95%-98%), followed by MSM (82%), general women (77%), IDUs (51%) and general men (42%). Most new HIV infections during 2011-2017 are expected to occur among general women (1666) and general men (977) followed by MSM (715). Bisexual men were estimated to contribute about 14% of the new HIV infections among general women in 2010 and this proportion was estimated to increase to 19% in 2017. Discussion: HIV prevention programs for MSM and the general population need to be strengthened. Ensuring early detection of HIV, and higher levels of consistent condom use by HIV-infected men and women are essential to prevent new HIV infections in future. %U http://www.ccsenet.org/journal/index.php/gjhs/article/view/18755