%0 Journal Article
%T Immune diagnosis of human fasciolosis in children from Cajamarca, Per迆
%A GEORGE V. HILLYER
%A MARICELIS SOLER DE GALANES
%A ELIO DELGADO AZAˋERO
%J Parasitolog赤a al d赤a
%D 2001
%I Scientific Electronic Library Online
%X The immunodiagnostic potential of a FAST-ELISA for the detection of antibodies in fasciolosis with sera from 6-12 year old children from Cajamarca, Peru was examined. Four children negative parasitologically were negative by FAST-ELISA. All 13 children found positive parasitologically were also positive by FAST-ELISA for 100% sensitivity. Twelve of the 13 infected children seroreverted 4 months post dihydroemetine therapy showing lower antibody levels as compared with the pretreatment sample. These results suggest that FAST-ELISA may be useful for the determination of infection and success of therapy in children with fasciolosis. Se estudio el potencial inmunodiagn車stico de un FAST-ELISA para la detecci車n de anticuerpos contra de fasciolosis en ni os de Cajamarca, Per迆. Sueros de 4 ni os no infectados fueron negativos mientras que 13 ni os infectados fueron positivos a la prueba de FAST-ELISA. Doce de los ni os infectados serorevirtieron con disminuci車n de anticuerpos cuatro meses luego de terapia con dehidroemetina. Estos resultados indican la utilidad de la prueba de FAST-ELISA para detecci車n de infecci車n y predicci車n de cura en ni os con fasciolosis.
%K Fasciola hepatica
%K Immunodiagnosis
%K FAST-ELISA
%K Fasciolosis in children
%U http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-07202001000300003