%0 Journal Article
%T Primary hyperparathyroidism: adenoma or hyperplasia
%A Betancourt-Piˋeres Aiken Felipe
%A Bonnet- Palencia Igor Iv芍n
%A Arias-Altamar Carlos Mauro
%A L車pez-Polo Daniela Patricia
%J Revista Ciencias Biom谷dicas
%D 2012
%I Universidad de Cartagena
%X Introduction: primary hyperparathyroidism (PH) is a symptomatic or asymptomaticclinical entity, characterized by the autonomous production of parathyroid hormone (PTH). Its classical presentation exhibits an increase of the serum calcium andparathyroid hormone levels. Parathyroid scintigrafy, among other imaging modalities,is frequently used to detect the hyperfunctioning glands.Clinical case: number 1. Female, 69 years old, asymptomatic, hypertension of recentonset, osteopenia, increased intact PTHi level and serum calcium concentration, andlow phosphate level, multinodular goiter (ultrasound), and focal increased uptake inthe inferolateral aspect of thyroid right lobe (parathyroid scintigraphy) consistent withparathyroid adenoma, confirmed by surgery and histopathology examination. Number2. Female, 69 years old, with history of chronic hypertension, nephrolithiasis andpartial thyroidectomy, actually with chronic diarrhea and headaches, erosive chronicduodenitis (endoscopy), increase of PTHi and serum calcium levels, changes in contrastneck CT scan and US consistent with thyroidectomy, and parathyroid scintigraphy withthree areas of focal increased isonitrile uptake consistent with parathyroid hyperplasia,confirmed by surgery and histopathologic findings.Conclusion: the parathyroid Scintigraphy (planar and Spect, double phase and doubletracer) done in combination, have good sensibility, specificity and diagnostic accuracyof parathyroid adenomas and hyperplasia, improving surgical procedures, with minimalincision or invasion, ad quality of life of hyperparathyroidism patients. Rev.cienc.biomed. 2012;3(2):350-354RESUMEN:Introducci車n: el hiperparatiroidismo primario (HP) es una entidad cl赤nica sintom芍ticao asintom芍tica, caracterizada por la producci車n aut車noma de parathormona (PTH).Se presenta elevaci車n del calcio s谷rico y de la parathormona (PTH), aunque esta迆ltima puede permanecer dentro en los rangos normales altos. La gammagraf赤a deparatiroides es uno de los estudios imagenol車gicos que se utiliza para localizar lasgl芍ndulas hiperfuncionantes.Casos cl赤nicos: n迆mero 1. Mujer de 69 a os, asintom芍tica, con hipertensi車n arterialde reciente comienzo y osteopenia. PTHi y calcio s谷rico elevados, f車sforo disminuido.Ecograf赤a de tiroides: bocio multinodular. Gammagraf赤a de paratiroides: hipercaptaci車nfocal del trazador, inferior y lateralmente al l車bulo derecho de la tiroides, compatible conadenoma paratiroideo. Realizada cirug赤a para resecci車n. Diagn車stico confirmado porhallazgos quir迆rgicos y de anatom赤a patol車gica. N迆mero 2. Mujer de 69 a os, hipertensi車ncr車
%K Hyperparathyroidism
%K Radionuclide Imaging
%K 99mTc-isonitrilos
%K Nuclear medicine
%K Parathyroid neoplasms
%K Parathyroid disease.
%U http://www.revistacienciasbiomedicas.com/index.php/revciencbiomed/article/view/223/181