%0 Journal Article
%T An alternative synthesis of (+) - propranolol and (+) ¨C atenolol
%A Aphiwat Teerawutgulrag
%J Maejo International Journal of Science and Technology
%D 2012
%I Maejo University
%X Herein, a simple synthesis pathway of beta-blockers starting from allyl amine ispresented. This synthesis features the opening of an epoxide ring with phenol derivatives followed by N-alkylation with iso-propylbromide to produce racemic propranolol and atenolol.
%K beta-blockers
%K propranolol
%K atenolol
%U http://www.mijst.mju.ac.th/vol6/372-378.pdf