%0 Journal Article %T Restoration of Innate and Adaptive Immune Responses by HCV Viral Inhibition with an Induction Approach Using Natural Interferon-Beta in Chronic Hepatitis C %A Y. Kishida %A N. Imaizumi %A H. Tanimura %A Y. Haruna %A S. Kashiwamura %A T. Kashiwagi %J Clinical and Developmental Immunology %D 2012 %I Hindawi Publishing Corporation %R 10.1155/2012/582716 %X Chronic hepatitis C (CHC) is a serious medical problem necessitating more effective treatment. This study investigated the hypothesis that an induction approach with nIFN-beta for 24 weeks followed by PEG-IFN-alpha %U http://www.hindawi.com/journals/cdi/2012/582716/