%0 Journal Article
%T Volumen nuclear de hepatocitos de h赤gados sometidos a un factor estimulante humoral en ratones isog谷nicos linea IOR Nuclear volume of hepatocytes in livers subjected to a humoral stimulating factor in isogenic rats, IOR line
%A Marielin Concepci車n Osorio
%A Pedro A D赤az Rojas
%J Revista Cubana de Investigaciones Biomˋˋdicas
%D 2013
%I ECIMED
%X Se estudi車 el comportamiento del volumen nuclear de los hepatocitos en 14 muestras del l車bulo medio de h赤gados de ratones isog谷nicos IOR que fueron sometidos a tres dosis de citosol de h赤gado regenerativo al inicio del experimento. Las muestras fueron tomadas durante ocho d赤as con frecuencia de doce horas. El corte se dividi車 en zonas proximal, medial y distal al hilio. Se aplico el m谷todo morfom谷trico para la determinaci車n del volumen nuclear de los hepatocitos a partir de su di芍metro mayor y menor. Los resultados mostraron que los valores m芍s altos del volumen nuclear esta en la zona proximal al hilio, aunque en todas las zonas existen diferencias significativas entre los valores obtenidos en la primera mitad de tiempo del experimento respecto a la parte final, con marcada orientaci車n a decrecer lo que puede ser debido a la presencia de factores humorales estimulantes en el citosol regenerativo. We studied the behavior of the nuclear volume of hepatocytes in 14 samples of the middle lobe of isogenic rats liver IOR that were subjected to three doses of regenerating liver cytosol at the beginning of the experiment. Samples were taken during eight days with a frequency of twelve hours. The incision was divided into the proximal, medial and distal to the ileum zones. The Morphometric method was applied to determine the nuclear volume of hepatocytes from its major and minor diameter. The results showed that the highest values of the nuclear volume are located in the proximal zone to the ileum, although in all zones there are significant differences between the values obtained in the first half of the experiment in relation to the final part, with marked orientation to decrease what can be due to the presence of stimulant humoral factors in the regenerative cytosol.
%K volumen nuclear
%K hepatocitos
%K regeneraci車n hep芍tica
%K nuclear volume
%K hepatocytes
%K liver regeneration
%U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-03002013000100009