%0 Journal Article
%T Steroid Nanocrystals Prepared Using the Nano Spray Dryer B-90
%A Koichi Baba
%A Kohji Nishida
%J Pharmaceutics
%D 2013
%I MDPI AG
%R 10.3390/pharmaceutics5010107
%X The Nano Spray Dryer B-90 offers a new, simple, and alternative approach for the production of drug nanocrystals. In this study, the preparation of steroid nanocrystals using the Nano Spray Dryer B-90 was demonstrated. The particle size was controlled by selecting the mesh aperture size. Submicrometer steroid particles in powder form were successfully obtained. These nanoparticles were confirmed to have a crystal structure using powder X-ray diffraction pattern analysis. Since drug nanocrystals have recently been considered as a novel type of drug formulation for drug delivery systems, this study will be useful for nano-medical applications.
%K steroid
%K fluorometholone
%K dexamethasone
%K drug nanocrystals
%K Nano Spray Dryer B-90
%U http://www.mdpi.com/1999-4923/5/1/107