%0 Journal Article
%T On a new law of bone remodeling based on damage elasticity: a thermodynamic approach
%A Idhammad Ahmed
%A Abdali Abdelmouna£żm
%J Theoretical Biology and Medical Modelling
%D 2012
%I BioMed Central
%R 10.1186/1742-4682-9-51
%X Background Bone tissue is the main element of the human skeleton and is a dynamic tissue that is continuously renewed by bone-resorbing osteoclasts and bone-forming osteoblasts. The bone is also capable of repairing itself and adapting its structure to changes in its load environment through the process of bone remodeling. Therefore, this phenomenon has been gaining increasing interest in the last years and many laws have been developed in order to simulate this process. Results In this paper, we develop a new law of bone remodeling in the context of damaged elastic by applying the thermodynamic approach in the case of small perturbations. The model is solved numerically by a finite difference method in the one-dimensional bone structure of a n-unit elements model. Conclusion In addition, several numerical simulations are presented that confirm the accuracy and effectiveness of the model.
%K Numerical simulation
%K Thermodynamic approach
%K Small perturbations hypothesis
%K Bone remodeling
%K Bone density
%K Damage
%K Fatigue
%K Osteocyte
%K Elasticity
%K N-unit elements
%U http://www.tbiomed.com/content/9/1/51