%0 Journal Article
%T The effect of green tea catechins as novel antithyroid compounds in hyperthyroid rabbits induced by levothyroxine sodium
%A Arwa H. AL-Saeed
%A Niran J. AL-Salihi
%A Iqbal J. AL-Assadi
%J Topclass Journal of Herbal Medicine
%D 2013
%I Topclass Global Enterprise
%X This study was undertaken to extract catechins from green tea leaves. It is to show the curative effect of green tea catechins after a short term daily oral administration for 8 days (200 mg?kg b.w) on serum level of thyroid hormones and thyroid-stimulating hormone in hyperthyroid rabbits induced by levothyroxine sodium (L-T4). Rabbits were divided into 4 groups, 6 rabbits in each group. Group 1 animals received only 3 ml normal saline orally as control group, group 2 was treated with (L-T4) 0.3 mg?kg b.w as hyperthyroidic. The 3rd group hyperthyroidic rabbits were post-treated with green tea catechins extract (200 mg?k g b.w) while the 4th group hyperthyroidic rabbits were post-treated with carbimazole (5 mg ? kg b.w). The results indicated high significantly increased (p< 0.001) in serum level of total triiodothyronine (TT3), total thyroxine (TT4) and high significantly stimulating hormone in hyperthyroid rabbits
%K Catechins
%K Hyperthyroidism
%K Green Tea
%U http://topclassglobaljournals.org/tjhm/pdf/2013/September/Al-Saeed%20et%20al.pdf