%0 Journal Article
%T Investigation of the anti-bacterial activity of Ageratum Conyzoides extract on microorganisms isolated from septic wound
%A Onuoha OG
%A Ayo JA
%A Osuagwu V
%A Iruolaje FO
%J Topclass Journal of Herbal Medicine
%D 2013
%I Topclass Global Enterprise
%X The active component of Ageratum Conyzoides was extracted using methanol, ethanol, distilled water, hexane, ethyl acetate and acetone solvents. Phytochemical analysis of the extracts showed the presence of the following components: alkaloids, tannins, saponins, glycoside, flavonoids, resins and anthraquinone. The susceptibility test of the extracts (methanol and ethanol) against septic wounds organism, implicate sensitivity of Staphylococcus and Escherichia coli. The methanol extract showed higher value of 28.00 mm for minimum inhibitory concentration than the ethanol extract test on all the fraction of the extract of methanol and ethanol obtained after column chromatography separation showed sensitivity to the test organisms. Infra-red spectroscopic analysis on the extract of methanol and ethanol showed high value of nitro-and ammonium based compounds. A. conyzoides is sensitive to organisms of septic wounds and could be used for cure of diseases. The presence of glycosides, nitro-ammonium-based compound is an indication of the nutrient potential of the extract as source of vitamins and protein respectively especially when used as food source
%K Ageratum Conyzoides
%K septic wound organisms
%K methanol and ethanol extract
%K nutrient potential
%U http://topclassglobaljournals.org/tjhm/pdf/2013/August/Onuoha%20et%20al.pdf