%0 Journal Article %T Oxidative Status and Plasma Prolidase Activity in Patients with Gallstones %A Alpaslan TERZ£¿ %A Sacit £¿OBAN %A Fahrettin YILDIZ %A Murat KAYA %J Trakya Universitesi Tip Fakultesi Dergisi %D 2010 %I %X Objective: The aim of our study was to investigate the oxidative and antioxidative status of plasma and plasma prolidase enzyme activity on gallstone disease. Material and Methods: The study group included 35 patient with gallstone disease and 30 healthy volunteers as control subjects. Plasma prolidase activity and oxidative-antioxidative parameters were measured. Antioxidative status of plasma was evaluated by measuring total antioxidant capacity. To determine oxidative status; total oxidant status and oxidative stress index were deermied. Results: Total antioxidant capacity levels of plasma were lower in the patients with gallstone disease than in controls (p<0.001). In contrast, total oxidant status levels and oxidative stress index values were higher in the patients than in controls (p<0.05 and p<0.001, respectively). Beside these, plasma prolidase activity was significantly lower in the patients than controls (p<0.001). Conclusions: The present results indicated that the oxidant parameters increased and antioxidant parameters decreased in patients with gallstones, and that these patients were exposed to oxidative stress. %K Gallstone disease %K oxidative status %K prolidase. %U http://www.tutfd.org/text.php3?id=341