%0 Journal Article %T Occurrence of Microcystis aeruginosa and microcystins in R¨ªo de la Plata river (Argentina) %A Dar¨ªo Andrinolo %A Paulo Pereira %A Leda Giannuzzi %A Claudia Aura %J Acta Toxicol¨®gica Argentina %D 2007 %I %X This paper is the first report on microcystins producer blooms of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata river, the most important drinking water supply of Argentina. The distribution of toxic cyanobacterium Microcystis cf. aeruginosa blooms in the Argentinean coast of the Rio de la Plata river was studied from December 2003 and January 2006. Microcystis aeruginosa persisted in the river with values ranged between 0 - 7.8 10(4) cells ml-1. Samples of two Microcystis aeruginosa water blooms were collected at La Plata river and were analyzed by the mouse bioassay and by high-performance liquid chromatography with Diode-array and MS detector. The samples showed high hepatotoxicity in mouse bioassay and, in accordance, important amount of microcystins. The bloom samples contained microcystins LR and a variant of microcystin with a molecular ion [M+H]+= 1037.8 m/z as major components. The total toxin content found in these samples was 0.94¦Ìg/mg and 0.69¦Ìg/mg of lyophilised cells. We conclude that the presence of toxic clones of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata is an actual sanitary and environmental problem and that further studies are necessary to make the risk assessment. %K Microcistys aeruginosa %K Bloom %K Rio de la Plata %K Hepatotoxins %K Microcystin %K HPLC-Diode array %U http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-37432007000100002