%0 Journal Article
%T Does localization of inflammatory process in Crohn's disease influence oral cavity changes? Czy lokalizacja procesu zapalnego w przebiegu choroby Le niowskiego-Crohna ma wp yw na zmiany w jamie ustnej?
%A Anna Paradowska
%A Marcin Braksator
%A Beata Kawala
%A Leszek Paradowski
%J Polish Gastroenterology
%D 2011
%I 
%X Introduction: Many of the diseases may have their manifestations in the oral cavity. A typical exampleof them are inflammatory bowel diseases (IBD). Typical systemic symptoms for IBD are: abdominalpain, diarrhea, rectal bleeding, loss of weight and signs of malnutrition. Crohn's disease (CD), as more severe is more frequently observed in the oral cavity of patients, especially at the exacerbation of the disease. These symptoms may precede and resemble other symptoms. Oral mucosa changes typically include: buccal cobblestoning, orofacial granulomatosis, lip swelling, hyperplastic changes, aphthae, cheilitis, stomatitis, changes of mucosa coloration, taste disorders and lichen planus. The changesmay be caused by malnutrition, but also may have their cause in incorrect function of autoimmunesystem (aphthae, buccal cobblestoning), or have genetic origin (geographic tongue).Aim of the study was to estimate the frequency of different types of oral cavity changes in patients suffering from Crohn's disease and to assess whether their nature and occurrence depends on the localization of the disease in the gastrointestinal tract in CD patients.Material and methods: In 18 patients with CD (8 female, 10 male, mean age 36.3¡À12.4 years), hospitalized due to exacerbation of the disease in the Department and Clinic of Gastroenterology and Hepatology of the Silesian Piasts Medical University in Wroc aw, Poland, dental examination was performed. The patients were chosen randomly. The localization of the disease in the gut was confirmed with endoscopic examination (gastro- and colonoscopy) and CT enteroclysis.Results: Among the patients, the disease was localized in the large bowel in 11 of them, while the smallbowel was affected in 15 individuals. Oral mucosa changes appeared in 14 out of 18 cases. None of the patients had more than 4 different lesions in the oral cavity. The most common were buccal cobblestoning (6 patients), recurrent aphthae (6) and lingua scrotalis (4). In 4 patients with CD no changes were observed. Surprisingly, the patients with localization of CD in the small intestine suffered from rarer oral manifestations of CD. Ten of 14 patients with any oral cavity changes had their disease localized in the large intestine. All the patients with aphthae had at least the large bowel involved.Conclusions: Oral mucosa changes occur in patients with CD very often, more frequently at the exacerbation of the disease. Changes at Crohn's disease can have immunologic (eg. aphthae, buccal cobblestoning) or genetic background (eg. lingua scrotalis) but also malnutriti
%K Crohn's disease
%K oral cavity
%K 0
%K 0
%K 
%U http://cornetis.pl/pliki/GP/2011/1/GP_2011_1_12.pdf