%0 Journal Article
%T Chitosonic£¿ Acid as a Novel Cosmetic Ingredient: Evaluation of its Antimicrobial, Antioxidant and Hydration Activities
%A Shu-Mei Lee
%A Kun-Ho Liu
%A Yen-Yu Liu
%A Yen-Po Chang
%A Chih-Chien Lin
%A Yi-Shyan Chen
%J Materials
%D 2013
%I MDPI AG
%R 10.3390/ma6041391
%X Chitosonic £¿ Acid, carboxymethyl hexanoyl chitosan, is a novel chitosan material that has recently been accepted by the Personal Care Products Council as a new cosmetic ingredient with the INCI (International Nomenclature of Cosmetic Ingredients) name Carboxymethyl Caprooyl Chitosan. In this study, we analyze several important cosmetic characteristics of Chitosonic £¿ Acid. Our results demonstrate that Chitosonic £¿ Acid is a water-soluble chitosan derivative with a high HLB value. Chitosonic £¿ Acid can form a nano-network structure when its concentration is higher than 0.5% and can self-assemble into a nanosphere structure when its concentration is lower than 0.2%. Chitosonic £¿ Acid has potent antimicrobial activities against gram-positive bacteria, gram-negative bacteria and fungus. Chitosonic £¿ Acid also has moderate DPPH radical scavenging activity. Additionally, Chitosonic £¿ Acid exhibits good hydration activity for absorbing and retaining water molecules with its hydrophilic groups. From a safety point of view, Chitosonic £¿ Acid has no cytotoxicity to L-929 cells if its concentration is less than 0.5%. Moreover, Chitosonic £¿ Acid has good compatibilities with various normal cosmetic ingredients. Therefore, we propose that Chitosonic £¿ Acid has the potential to be a widely used ingredient in various types of cosmetic products.
%K antimicrobial activity
%K antioxidant activity
%K Carboxymethyl Caprooyl Chitosan
%K Chitosonic£¿ Acid
%K cosmetic ingredient
%K hydration activity
%U http://www.mdpi.com/1996-1944/6/4/1391