%0 Journal Article
%T Synthesis and Antimicrobial Evaluation of Certain Novel Thiazoles
%A Meesaraganda Sreedevi
%A Aluru Raghavendra Guru Prasad
%A Yadati Narasimha Spoorthy
%A Lakshmana Rao Krishna Rao Ravindranath
%J Advanced Pharmaceutical Bulletin
%D 2013
%I Tabriz University of Medical Sciences
%X Purpose: This article makes an attempt to synthesize certain compounds containing thiazole and imidazole moieties and screen for the antimicrobial properties. Methods: The novel compounds synthesized were characterized by elemental analysis, IR and 1HNMR spectral data. The antimicrobial activity of novel compounds was evaluated by cup plate method. Results: The compound p-t showed more antibacterial activity than that of the standard. p-hp and p-as showed considerable antibacterial activity. p-t demonstrated higher antifungal activity than that of the standard while p-hp and p-as showed considerable antifungal activity. Conclusion: The antimicrobial activity studies were conducted on certain selected bacteria and fungi. In each case antimicrobial activity of the compounds was compared with that of standards. p-t, p-hp, p-np, p-cp, p-ts and p-as showed considerable antimicrobial activity.
%K Imidazole moiety
%K Thiazole moiety
%K Synthesis
%K Characterization
%K Antimicrobial activity
%U http://journals.tbzmed.ac.ir/PDF/APB/Manuscript/APB-3-227.pdf