%0 Journal Article
%T Significance of decoy receptor 3 (Dcr3) and external-signal regulated kinase 1/2 (Erk1/2) in gastric cancer
%A Donghai Yang
%A Xin Fan
%A Ping Yin
%A Qiang Wen
%A Feng Yan
%A Sibo Yuan
%A Bin Liu
%A Guohong Zhuang
%A Zhongchen Liu
%J BMC Immunology
%D 2012
%I BioMed Central
%R 10.1186/1471-2172-13-28
%X The expression of DcR3 and ERK1/2 in tumor tissues of gastric cancer patients was significantly higher than the non-cancerous group (P£¿<£¿0.05). There was no statistical difference among tumor tissues from patients with different ages or gender, and even of different differentiation (P£¿>£¿0.05). However, in patients with stage I gastric cancer, the DcR3 and ERK1/2 levels were significantly lower than patients with more advanced stages.DcR3 and ERK1/2 play a vital role in the development of gastric cancer, and they may be new markers for indicating the efficiency of gastric cancer treatment in the future.
%U http://www.biomedcentral.com/1471-2172/13/28/abstract