%0 Journal Article
%T Squamous cell carcinoma in mature cystic teratoma of the ovary
%A Amid£¿i£¿ Jelena
%A £¿olai Matilda
%A Mocko-Ka£¿anski Mihaela
%A Gluhovi£¿ Aleksandar
%J Medicinski Pregled
%D 2012
%I Serbian Medical Society, Society of Physicians of Vojvodina, Novi Sad
%R 10.2298/mpns1210429a
%X Introduction. Malignant transformation is a rare complication of mature cystic teratoma, with squamous cell carcinoma as the most common malignancy (in 75% of cases). In this article we present a case of a well-differentiated squamous cell carcinoma arising in a mature cystic teratoma and discuss the morphological and clinico-pathological features of malignant transformation in teratoma. Case Report. An 80-year-old woman with symptoms of acute abdomen underwent left salpingo-oophorectomy. Gross examination showed a cystic mass measuring 20 cm in diameter, with papillary formation on its internal surface. Histology revealed a well-differentiated squamous cell carcinoma arising in mature cystic teratoma. Squamous epithelium surrounding the tumor was dysplastic. Conclusion. Squamous cell carcinoma in mature cystic teratoma is a rare pathologic event and in most cases it is an accidental pathohistological finding.
%K Carcinoma
%K Squamous Cell
%K Teratoma
%K Ovarian Cysts + pathology
%K Ovarian Neoplasms + pathology
%K Cell Transformation
%K Neoplastic
%K Female
%K Aged
%K 80 and over
%U http://www.doiserbia.nb.rs/img/doi/0025-8105/2012/0025-81051210429A.pdf