%0 Journal Article %T Rola czynnik¨®w genetycznych, autoimmunologicznych, infekcyjnych i hormonalnych w etiopatogenezie liszaja twardzinowego ¨C przegl d pi miennictwa %A Agnieszka Cegielska %A Beata Imko-Walczuk %A Janusz Ja£¿kiewicz %A Waldemar Placek %J Przegl£¿d Dermatologiczny %D 2011 %I Termedia Publishing House %X Lichen sclerosus (LS) is a chronic inflammatory disease with a characteristicclinical appearance and specific histopathology. Clinically ischaracterized by plaques of ivory white atrophic lesions licalized,chiefly on genitals, and also in extragenital localisation. Both males andfemales at any age are affected. The aetiology of LS remains unclear. Inthe literature, the hypothesis of possible role of genetic, autoimmune,infectious and hormonal factors are found. Oxidative stress may alsoplay additional role. Understanding of lichen sclerosus pathogenesismay improve its therapy and allow to avoid its complications. %K lichen sclerosus at atrophicus %K lichen sclerosus %K etiopathogenesis %K HLA %K ECM1 %K hormons %K oxidative stress %U http://www.termedia.pl/Rola-czynnikow-genetycznych-autoimmunologicznych-infekcyjnych-i-hormonalnych-r-nw-etiopatogenezie-liszaja-twardzinowego-przeglad-pismiennictwa,56,17132,1,0.html