%0 Journal Article
%T Rola limfocyt¨®w T regulatorowych w patogenezie wybranych chor¨®b p cherzowych
%A Anna Ja£¿ocha-Kaczka
%A Agnieszka £¿ebrowska
%A El£¿bieta Waszczykowska
%J Przegl£¿d Dermatologiczny
%D 2011
%I Termedia Publishing House
%X Regulatory T cells (Treg) are a phenotypically heterogeneous group ofcells, playing an important role in regulation of the immune response.To date, several subtypes of regulatory cells have been identified. Themost important of them are: lymphocytes CD4+CD25+, Tr1, Th3 andNK cells. Regulatory T lymphocytes act by secretion of suppressivecytokines (IL-10, TGF-¦Â) or direct cell-to-cell interaction. Functionalabnormalities of regulatory T cells are important in pathogenesis ofmany diseases, especially autoimmune ones. Based on published studies,the review discusses the role of regulatory T cells in pathogenesisof selected bullous skin diseases.
%K bullous diseases
%K regulatory T cells
%K immune response regulation
%U http://www.termedia.pl/Prace-pogladowe-Rola-limfocytow-T-regulatorowych-w-patogenezie-wybranych-chorob-pecherzowych,56,17004,1,0.html