%0 Journal Article
%T Secondary acute myeloid leukemia after successful treatment for osteosarcoma
%A Mittal Rakesh
%A Ramaswamy N
%A Pandita R
%A Al Bahar S
%J Indian Journal of Medical and Paediatric Oncology
%D 2010
%I Medknow Publications
%X Secondary acute myeloid leukemia (sAML) is a rare complication following chemotherapy for osteogenic sarcoma. However, the exact offending drug is difficult to prove as there is no consistent data. It usually develops 2 years after completion of therapy. We report a case of sAML that developed within 8 months of completing the treatment. The patient was treated with cisplatin, doxorubicin and high-dose methotreaxate followed by surgery (amputation). Eight months after completion of therapy, while on follow-up, he presented with leukocytosis and thrombocytopenia and confirmed to have AML.
%K Acute myeloid leukemia
%K chemotherapy
%K osteosarcoma
%K secondary malignancy
%U http://www.ijmpo.org/article.asp?issn=0971-5851;year=2010;volume=31;issue=1;spage=33;epage=35;aulast=Mittal