%0 Journal Article
%T Ceftriaxone resistant Shigella Flexneri, an emerging problem
%A Gupta Soham
%A Mishra Baijayanti
%A Muralidharan Sethumadhavan
%A Srinivasa Hiresave
%J Indian Journal of Medical Sciences
%D 2010
%I Medknow Publications
%X Shigellosis is a disease of public health importance in developing countries. It may cause self-limited diarrhea to severe dysentery. Emergence of multi drug resistant (MDR) strains is a growing concern globally. Ceftriaxone and ciprofloxacin are the drugs of choice for MDR cases. Here, we report a case of MDR Shigella flexneri from an immunocompromised patient. The strain was resistant to ceftriaxone [minimum inhibitory concentration (MIC) ¡Ý 64 ¦Ìg/ml], limiting the treatment option. Simultaneously, the strain was also found to be resistant to ciprofloxacin (MIC ¡Ý 4 ¦Ìg/ml). However, it was susceptible to ceftazidime (MIC 4 ¦Ìg/ml). This is the first case of ceftriaxone resistant Shigella spp. reported from our hospital.
%K Ceftriaxone
%K extended spectrum beta lactamase
%K minimum inhibitory concentration
%K multi drug resistant
%K Shigella flexneri
%U http://www.indianjmedsci.org/article.asp?issn=0019-5359;year=2010;volume=64;issue=12;spage=556;epage=559;aulast=Gupta