%0 Journal Article
%T Editorial
%A Bagel J
%J Psoriasis: Targets and Therapy
%D 2011
%I Dove Medical Press
%X Jerry BagelPsoriasis Treatment Center of Central New Jersey, East Windsor, NJ, USATwenty-five years ago, inpatient Goekerman therapy was considered to be the "gold standard" treatment for psoriasis. We thought PUVA (psoralen + ultraviolet A light) worked because it intercalated keratinocytes inhibiting cell division, methotrexate affected keratinocytic proliferation, and broadband ultraviolet B creating thymine dimers which also prevented keratinocytic proliferation. The idea that psoriasis was an immunologic disease was in its embryonic development.
%U http://www.dovepress.com/editorial-psoriasis-targets-and-therapy-a7720