%0 Journal Article
%T Tos ferina neonatal, una enfermedad emergente Newborn pertussis: a re-emergent disease
%A 芍ngela Mar赤a Alb芍n
%A Fabio Ernesto Arcos
%A Freddy Andr谷s Barrios
%A Juan Manuel V芍squez-Jim谷nez
%J Infectio
%D 2012
%I Asociacion Colombiana de Infectologia
%X La tos ferina es una enfermedad del tracto respiratorio superior que ha incrementado 迆ltimamente su incidencia. Se ha demostrado que los adultos son la principal fuente de transmisi車n para los ni os susceptibles. En la actualidad, la enfermedad afecta con m芍s frecuencia a los ni os menores de 3 meses, entre los cuales, los menores de 1 mes tienen mayor riesgo de complicaciones y letalidad. Se presenta un caso aut車ctono de una reci谷n nacida de 16 d赤as con episodios de tos quintosa, cianosante y emetizante, cuadro hem芍tico que evidencia leucocitosis y linfocitosis, que se origin車 en un 芍rea donde est芍 implementada, como pol赤tica de salud p迆blica, la vacunaci車n para tos ferina en ni os. La paciente tuvo una evoluci車n t車rpida complicada con convulsiones y necesidad de ventilaci車n mec芍nica. Se identific車 en la paciente Bordetella pertussis por inmunofluorescencia, reacci車n en cadena de la polimerasa y cultivo. Se hace una breve revisi車n de la literatura, haciendo 谷nfasis en el panorama actual de la vacunaci車n en neonatos. Neonatal pertussis is an upper respiratory tract infection whose incidence has recently increased. Adults have been demonstrated to be the main source for neonatal infection, accounting for the rising rates of disease in this later population group. Currently, the disease affects chiefly infants under three months of age, among which, those younger than one moth have the highest rates of complication and death. Here we present an indigenous case of a 16 days old newborn that arose in an area where pertussis vaccination during the first months of life is the rule and very few cases had been documented throughout the last years. The patient presented whooping cough with cyanosis and emesis episodes, whose complete blood count showed markedly and increasingly high leukocytosis and lymphocytosis. Her clinical course complicated with seizures and required mechanical ventilation. B. pertussis was demonstrated by means of immunofluorescence, polymerase chain reaction and culture. A brief literature review is made with emphasis on current landmarks on pertussis vaccination.
%K Tos ferina
%K Tos parox赤stica
%K Leucocitosis
%K Inmunofluorescencia
%K Vacunaci車n
%K Pertussis
%K Whooping cough
%K Leukocytosis
%K Immunofluorescence
%K Vaccination
%U http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0123-93922012000300010