%0 Journal Article %T Evaluation of health related quality of life in irritable bowel syndrome patients %A Raika Jamali %A Arsia Jamali %A Maryam Poorrahnama %A Abdollah Omidi %A Bardia Jamali %A Neda Moslemi %A Reza Ansari %A Shahab Dolatshahi %A Naser Ebrahimi Daryani %J Health and Quality of Life Outcomes %D 2012 %I BioMed Central %R 10.1186/1477-7525-10-12 %X This cross sectional study included two hundred and fifty IBS patients with the mean age (¡À standard deviation) of 31.62 (¡À 11.93) years that were referred to outpatient gastroenterology clinic. IBS patients were diagnosed based on Rome-3 criteria by a gastroenterologist, and then they were categorized into three subtypes according to the predominant type of bowel habit. The "QOL specific for IBS", "Stait-trait anxiety inventory", and "Beck depression inventory-2" questioners were used to evaluate QOL, anxiety, and depression symptoms, respectively.The mean QOL scores in IBS mixed subtype (71.7 ¡À 25.57), constipation predominant subtype (80.28 ¡À 25.57), and diarrhea predominant subtype (76.43 ¡À 19.13) were not different. (P value: 0.05) In multivariate linear regression analysis, anxiety symptom scores were inversely correlated with QOL scores. [Standardized beta: -0.43, (95% confidence interval: -0.70, -0.39), P value: < 0.01]It seems reasonable to manage anxiety symptoms properly in IBS patients since this might increase their QOL.Irritable Bowel Syndrome (IBS) is a common gastrointestinal disease [1]. It is associated with significant direct health-care costs and indirect costs related to impaired work productivity [2]. IBS patients are diagnosed based on Rome criteria and are categorized into different subtypes according to the predominant type of bowel habit [3].IBS seems to have a great impact on the health related quality of life (QOL) of the patients [4]. The use of health related QOL assessments have come to interest for better understanding of the biopsychosocial model in the functional gastrointestinal disorders [5].Controversy exists in results of previous studies about QOL in different IBS subtypes [6-11]. This finding might be related to differences in cultural (such as genetic, nutritional, and socio-demographical) and psychiatric co-morbidities (such as depression and generalized anxiety disorder) in the studied populations.It seems reasonable to det %K Quality of life %K Irritable bowel syndrome %K Gender %K Anxiety %K Depression %U http://www.hqlo.com/content/10/1/12