%0 Journal Article
%T Mortality and health-related quality of life in prevalent dialysis patients: Comparison between 12-items and 36-items short-form health survey
%A Tone Brit H £¿sthus
%A Valjbona T Preljevic
%A Leiv Sandvik
%A Torbj£¿rn Leivestad
%A Inger Hilde Nordhus
%A Toril Dammen
%A Ingrid Os
%J Health and Quality of Life Outcomes
%D 2012
%I BioMed Central
%R 10.1186/1477-7525-10-46
%X The Short-Form Health Survey (SF-36) with the embedded SF-12 was applied in 301 dialysis patients cross-sectionally. Physical and mental component summary (PCS-36, MCS-36, PCS-12, and MCS-12) scores were calculated. Clinical and demographic data were collected. Mortality (followed for up to 4.5£¿years) was analyzed with Kaplan Meier plots and Cox proportional hazards, after censoring for renal transplantation. Exclusion factors were observation time <2£¿months (n£¿=£¿21) and missing component summary scores (n£¿=£¿10 for SF-36; n£¿=£¿28 for SF-12), thus 252 patient were included in the analyses.In 252 patients (60.2£¿¡À£¿15.5£¿years, 65.9% males, dialysis vintage 9.0, IQR 5.0-23.0£¿months), mortality during follow-up was 33.7%.(85 deaths). Significant correlations were observed between PCS-36 and PCS-12 (¦Ñ£¿=£¿0.93, p£¿<£¿0.001) and between MCS-36 and MCS-12 (¦Ñ£¿=£¿0.95, p£¿<£¿0.001). Mortality rate was highest in patients in the lowest quartile of PCS-12 (¦Ö2£¿=£¿15.3, p£¿=£¿0.002) and PCS-36 (¦Ö2£¿=£¿16.7, p£¿=£¿0.001). MCS was not associated with mortality. Adjusted hazard ratios for mortality were 2.5 (95% CI 1.0-6.3, PCS-12) and 2.7 (1.1 ¨C 6.4, PCS-36) for the lowest compared with the highest (¡°best perceived¡±) quartile of PCS.Compromised HRQOL is an independent predictor of poor outcome in dialysis patients. The SF-12 provided similar predictions of mortality as SF-36, and may serve as an applicable clinical tool because it requires less time to complete.
%K Chronic kidney disease
%K Dialysis
%K Health-related quality of life
%K Mortality
%K Physical component summary score
%K SF-12 and SF-36
%U http://www.hqlo.com/content/10/1/46/abstract