%0 Journal Article
%T The influence of deoxynivalenol (DON) on hemoleucogram components at rats
%A Marioara Nicoleta FILIMON
%A Adrian SINITEAN
%A Nicoleta IANOVICI
%A Aurica BOROZAN
%J Analele Universitatii din Oradea, Fascicula Biologie
%D 2012
%I University of Oradea Publishing House
%X Mycotoxins are considered to be natural substances produced by fungi, infecting cereals and other agricultural products. The study was conducted on 20 male Sprague-Dowley rats which received feed with known concentration of DON. The animals were divided in 4 groups: Group I - control group, group II - 3 mg//Kgc DON, group III - 5 mg/Kgc DON, group IV - 9 mg/Kgc DON. The blood samples were taken and the main components of bloods were analyzed: erythrocytes, platelets, leucocytes, Ht. (hematocrit), Hb. (concentration hemoglobin). Variations of blood parameters give information regarding the influence of DON on functionality of cardiovascular and excretory system. Administration of DON contaminated feeds determined at Sprague-Dowley rats a decrease of erythrocytes and platelets with each increasing dose (p < 0.05), a decrease of hematocrit and concentration of hemoglobin and no significant changes (p > 0.05) were observed regarding the number of leucocytes.
%K mycotoxin
%K deoxynivalenol
%K rat
%K hemoleucogram
%U http://www.bioresearch.ro/bioresearch/2012-1/023-028-AUOFB.19.1.2012-FILIMON.M.N.-West.Univ.Biol.Tm.Ro.-The.influence.of.deohznivalenol.pdf