%0 Journal Article
%T Understanding asthma and the metabolic syndrome - a Nigerian report
%A OLUFUNKE O ADEYEYE
%A ANTHONIA O OGBERA
%A OLAYINKA O OGUNLEYE
%A AYODEJI T BRODIE-MENS
%A FOLASADE F BOLARINWA
%A RAYMOND T BAMISILE
%A BABATUNDE O ONADEKO
%J International Archives of Medicine
%D 2012
%I BioMed Central
%R 10.1186/1755-7682-5-20
%X This cross-sectional study was carried out at the asthma clinic of a tertiary teaching hospital. Ethical clearance was obtained from the research and ethics committee of the hospital. Written consent was obtained from the participants. Interviewer based questionnaire was used to obtain required information, anthropometric indices were recorded and clinical examinations done. Pulmonary function tests were carried out using desktop Alpha Spirometer model 6000 made by Vitalograph UK (2007). Blood pressure was measured using sphygmomanometer in mmHg. Fasting venous blood was taken for blood sugar and lipid profile. Metabolic syndrome was defined by the international diabetes Federation (IDF) criteria.One hundred and fifty eight (158) asthmatics participated in the study comprising of 63 (39.9%) males and 95(60.1%) females. The age range was 14-78 years with a mean of 46.48+/-17.00 years. The mean duration of asthma diagnosis was 13.95+/-12.14 years. The prevalence of hypertension was 29.1%. 17 (10.8%) had fasting blood sugar above 100 mg/dl. Abdominal obesity was present in 78 (49.5%). The mean total cholesterol was 192.63+/-40.7 mg/dl. HDL was low in 21(22%) of female and 3 (4.8%) male. The prevalence of metabolic syndrome was 17.7%, affecting 28 asthma patients. Asthma control was affected by the presence of metabolic syndrome. P£¿<£¿0.05. The pulmonary function test was not significantly affected by presence of metabolic syndrome.Metabolic syndrome prevalence is high in the population of asthma patients studied. It is therefore important to screen patient with asthma for this condition and treat to improve outcome.
%U http://www.intarchmed.com/content/5/1/20/abstract