%0 Journal Article
%T Separation of Short Single- and Double-Stranded DNA Based on Their Adsorption Kinetics Difference on Graphene Oxide
%A Po-Jung Jimmy Huang
%A Juewen Liu
%J Nanomaterials
%D 2013
%I MDPI AG
%R 10.3390/nano3020221
%X Separation of short single- and double-stranded DNA typically requires gel electrophoresis followed by DNA extraction, which is a time consuming process. Graphene oxide adsorbs single-stranded DNA more quickly than double-stranded ones, allowing for selective removal of the former with a simple mixing and centrifugation operation. The effect of DNA length and salt on adsorption selectivity has been characterized and its application in DNA melting curve measurement has been demonstrated.
%K graphene
%K DNA
%K adsorption
%K fluorescence
%K separation
%K gel electrophoresis
%U http://www.mdpi.com/2079-4991/3/2/221