%0 Journal Article
%T The role of vitamin D in children with recurrent Tonsillopharyngitis
%A Ismail Y£¿ld£¿z
%A Emin Unuvar
%A Umit Zeybek
%A Bahar Toptas
%A Sad£¿k Toprak
%A Canan Cacina
%A Ayse Kilic
%A Salih Aydin
%J Italian Journal of Pediatrics
%D 2012
%I BioMed Central
%R 10.1186/1824-7288-38-25
%X Eighty-four children with recurrent tonsillitis and seventy-one healthy children aging between 2 and 10£¿years were enrolled in this study. Serum 25-OH vitamin D level was measured with ELISA and vitamin D receptor gene polymorphism (Apa1, Taq 1, Fok1) was determined by PCR. Serum 25-OH vitamin D level below 50£¿nmol/L was accepted as deficiency. The vitamin D receptor gene polymorphism in each group was compared.The mean age was 5.6 ¡À 2.4 and 6.1£¿¡À£¿2.7£¿years in study and control group, respectively. The average serum 25-OH vitamin D level was 142.7£¿¡À£¿68.1£¿nmol/L in study group and 192.3£¿¡À£¿56.1£¿nmol/L in control group. There was significant difference between the groups (p < 0.01). In study group, 4.7% (n£¿=£¿4) of children had serum 25 OH vitamin D levels below 50£¿nmol/L. None of the children in control group had serum 25-OH vitamin D level below 50£¿nmol/L. There was no significant differences in vitamin D receptor gene polymorphisms between groups.Serum 25-OH vitamin D levels in recurrent tonsillitis group were lower than those in healthy children. But, there was no difference in the incidence of vitamin D receptor gene polymorphism between the two groups.
%K Child
%K Vitamin D
%K Infection
%K Tonsillitis
%U http://www.ijponline.net/content/38/1/25/abstract