%0 Journal Article
%T L¡¯argon : utilisations, toxicit¨¦ et strat¨¦gie analytique en toxicologie m¨¦dicol¨¦gale Argon: Uses, toxicity and analytical strategy in forensic toxicology. A review
%A Varlet Vincent
%A Bouvet Alain
%A Augsburger Marc
%J Annales de Toxicologie Analytique
%D 2013
%I 
%R 10.1051/ata/2013025
%X Bien qu¡¯intrins¨¨quement non toxiques, les gaz nobles comme l¡¯argon entra nent ¨¤ fortes concentrations une d¨¦pl¨¦tion d¡¯oxyg¨¨ne pouvant mener jusqu¡¯¨¤ l¡¯asphyxie. Si l¡¯argon se retrouve dans la circulation g¨¦n¨¦rale, celui-ci peut m¨ºme ¨ºtre responsable d¡¯embolies parfois fatales. Cependant, les propri¨¦t¨¦s d¡¯inerties physicochimiques de ce gaz le rendent tr¨¨s utile dans de nombreuses applications actuelles. Ces applications ¨¦tant en constante augmentation, il n¡¯est pas rare d¡¯observer proportionnellement des intoxications parfois l¨¦tales li¨¦es ¨¤ ce gaz. Ainsi, devant le manque d¡¯harmonisation des pr¨¦l¨¨vements d¡¯¨¦chantillons biologiques afin de mettre en ¨¦vidence de telles intoxications aux gaz nobles et devant l¡¯augmentation du nombre de cas, il devient n¨¦cessaire d¡¯¨¦tablir un ¨¦tat des lieux sur l¡¯utilisation de l¡¯argon, sa toxicit¨¦ et la strat¨¦gie analytique ¨¤ adopter dans le contexte m¨¦dico-l¨¦gal. Even though noble gases such as argon are intrisically non-toxic, they will enhance an oxygen-depletion at high concentrations. This depletion may lead to asphyxia. If argon is found in blood flow, it could be responsible of an embolism. However, its inert physicochemical properties appear to be very useful to a wide range of current applications. The rise of these applications induces a proportionnal increase of lethal intoxications due to this gas. Thus, as no standardization of biological samples exists, and knowing the increase of argon intoxication cases, it seems necessary to establish an incoming inventory of fixture concerning the use of argon. It will confirm its toxicity properties and will highlight other intoxications due to noble gas. This should lead to a new analytical strategy suitable to the forensic context.
%K Argon
%K gaz noble
%K ¨¦chantillonnage de gaz
%K analyse de gaz
%K Argon
%K noble gases
%K gas sampling
%K gas analysis
%U http://dx.doi.org/10.1051/ata/2013025