%0 Journal Article
%T Right ventricular dysfunction following continuous flow left ventriccular assist device placement in 51 patients: predicators and outcomes
%A Siyamek Neragi-Miandoab
%A Daniel Doldstein
%A Ricardo Bello
%A Robert Michler
%A David D'Alessandro
%J Journal of Cardiothoracic Surgery
%D 2012
%I BioMed Central
%R 10.1186/1749-8090-7-60
%X The aim of the study is to investigate the significance of pre-existing RV dysfunction, tricuspid valve (TV) insufficiency, and the severity of septal deviation following LVAD implantation on RV dysfunction, as well as the outcome and short-term complications in 51 patients from June 2006 to August 2010. Student t test was used to compare the data and estimate the p value.Mean age was 55.1 ¡À 13, with a male to female ratio of 3.25. The 30-day mortality was 13.7% (7/51 patients), and the overall mortality was 23.5% (12/51 patients). Meanwhile, 21 patients (21/51; 41.2%) have undergone orthotopic heart transplantation. The mean time of support was 314.5¡À235£¿days with a median of 240£¿days at the time of closing this study. Echocardiographic evaluation of RV function pre- and post-implantation of an LVAD demonstrated septal deviation towards the left ventricle in immediate postoperative phase, which correlated with acute RV dysfunction (p£¿=£¿0.002). Preoperative RV dysfunction was a significant predictor of postoperative right heart dysfunction following implantation of an LVAD (p£¿=£¿0.001).Preoperative RV dysfunction is a predictor of RV failure in LVAD patients. The adjustment of septal deviation through gradual increase of the LVAD flow can prevent the acute RV dysfunction following LVAD placement.
%K right heart failure
%K congestive heart failure
%K septal function
%K tricuspid valve
%K regurgitation
%U http://www.cardiothoracicsurgery.org/content/7/1/60/abstract