%0 Journal Article
%T Pharmacological evaluation of Jatropha curcas L. extract for Anti-diarrhoeal Activity
%A Kamal Sachdeva
%A Preeti Garg
%A Manmohan Singhal
%A Birendra Srivastava
%J Research in Pharmacy
%D 2012
%I GKS Publisher
%X The present study provides the pharmacological evaluation of stem bark extract ofJatropha curcas L. for anti-diarrhoeal activity in rats. We made an attempt to study theeffect of stem bark extract of Jatropha curcas L. on diarrhoeal disease. The differentactivities studied were castor oil-induced diarrhoea, magnesium sulphate induceddiarrhoea and charcoal meal transit test. The result of the study reflected that methanolextract of the stem bark (100, 300 mg/kg) decreased total no. of faeces, wet faeces anddistance travelled by charcoal plug and showed the anti-diarrhoeal activity. Jatrophacurcas L. extract demonstrates the anti-diarrhoeal activity in rats.
%K Castor oil-induced diarrhoea
%K charcoal meal transit test
%K diarrhoeal
%K Jatropha curcas
%K magnesium sulphate induced diarrhoea
%U http://www.researchinpharmacy.com/view/article/4/2/1