%0 Journal Article
%T Diagnosis and prognosis evaluation of 1,2-dichloroethane encephalopathy - Magnetic resonance imaging combined with diffusion tensor imaging and magnetic resonance spectroscopy study
%A Zhan Fulan
%A Zheng Wenbin
%A Liu Lian
%A Kong Lingmei
%J Neurology India
%D 2011
%I Medknow Publications
%X Neuroimaging findings in 1,2-dichloroethane (1,2-DCE) encephalopathy have seldom been reported. We present the comprehensive neuroimaging findings, conventional magnetic resonance imaging (MRI) combined with diffusion tensor imaging (DTI) and 1 H-magnetic resonance spectroscopy ( 1 H-MRS), in a case of 1,2-DCE encephalopathy. On day-4 the signal intensity of the lesions on diffusion-weighted imaging (DWI) was higher than that with T2-weighted imaging (T2WI); mean apparent diffusion coefficient (ADC) values for lesions were lower than control values. On day-20, the mean ADC value was increased gradually, whereas the mean fractional anisotropy (FA) of the lesions was significantly reduced. 1 H-MRS showed reduced ratios of N-acetyl aspartate to creatinine (NAA/Cr) and NAA to choline (NAA/Cho) on day-20 as compared with the control values. Combining conventional MRI with DTI and MRS is valuable in the early diagnosis and prognosis of 1,2-DCE-induced encephalopathy.
%K 1
%K 2-Dichloroethane poisoning
%K DTI
%K encephalopathy
%K MR spectroscopy
%U http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2011;volume=59;issue=1;spage=108;epage=110;aulast=Zhan