%0 Journal Article
%T Glycogen hepatopathy in a 13-year-old male with type 1 diabetes
%A Aljabri Khalid
%A Bokhari Samia
%A Fageeh Sanaa
%A Alharbi Abdullah
%J Annals of Saudi Medicine
%D 2011
%I King Faisal Specialist Hospital and Research Centre
%X Glycogenic hepatopathy (GH ) is a rare cause of serum transaminase elevations in type 1 diabetes mellitus. We describe a 13-year-old male with a history of poorly controlled type 1 diabetes mellitus who presented with hepatomegaly and severe transaminase flares. Liver histology confirmed GH. Treatment consists of improving glycemic control. Hepatomegaly due to excess glycogen storage in poorly controlled type 1 diabetics has been associated with younger patients with poor glycemic control, occurring about 2-4 weeks after starting insulin treatment, and resolving upon glucose stabilization. We conclude that glycogenic hepatopathy can cause hepatomegaly and significant transaminase elevations in individuals with type I diabetes mellitus, The recovery of severe transaminase elevations in this patient illustrates the more benign course of GH, which is a condition with a far better prognosis. Clinician awareness of GH should prevent diagnostic delay and will provide better insight into the prevalence of GH.
%U http://www.saudiannals.net/article.asp?issn=0256-4947;year=2011;volume=31;issue=4;spage=424;epage=427;aulast=Aljabri