%0 Journal Article
%T Role of antileukotrienes in acute asthma exacerbations
%A Domenico Lorenzo Urso
%A Daniele Vincenzo
%A Lorenzo Formaro
%A Ada Federico
%J Reviews in Health Care
%D 2012
%I SEEd
%R 10.7175/rhc.v3i2.155
%X Acute asthma exacerbations are one of the most frequent reasons to visit the emergency department or general practitioner. Although current standard treatments for acute asthma ¨C including supplemental oxygen, short-acting ¦Â2-agonists, systemic corticosteroids and anticholinergics ¨C are quite effective in most patients, they are inadequate for rapid and sustained improvement in a significant proportion. The antileukotrienes, a relatively new class of drugs, have a role in the treatment of chronic asthma. Their relatively rapid onset of action after endovenous or oral administration and their additive effect to ¦Â2-agonists led to the hypothesis that they might be of benefit in acute asthma. This review examines the efficacy of antileukotrienes in the treatment of acute asthma.
%K Acute asthma
%K Antileukotrienes
%K Cysteinil-leukotrienes
%K Airways inflammation
%U http://journals.edizioniseed.it/index.php/rhc/article/view/155