%0 Journal Article
%T Synthesis and Antimicrobial Evaluation of some2-Azetidinone derivatives
%A S.Jubie*
%A B.Gowramma
%A Nitin K.Muthal
%A R.Kalirajan
%A S.Gomathi and K.Elango.
%J International Journal of ChemTech Research
%D 2009
%I Sphinx Knowledge House
%X In our present study p-anisidine is condensed with different substituted aromatic aldehydes to form respective schiff bases. The schiff bases are cyclised with chloroacetylchloride in triethylamine to yield the corresponding 2-azetidinones. Structures of synthesized compounds are confirmed by physical & spectral analysis. The compounds are evaluated for their antimicrobial properties. The activities are due to C=O, C-N, linkages in 2-azetidinones. All the compounds have shown comparable antimicrobial activities. Among these one 2-azetidinone having 2, 4 dimethyl amino phenyl at 2nd position have shown good activity in all the species.
%K 2-azetidinones
%K antimicrobial activity
%K schiff bases
%U http://sphinxsai.com/pdf/jct_Ap_Ju_09/CT=7%20S.Jubie%20(153-157).pdf