%0 Journal Article
%T Seasonality of thrombogenic disorders in coronary atherosclerosis recrudescence
%A Svetlana S. Parshina
%A Tatyana N. Afanasyeva
%A Liliana K. Tokaeva
%J Russian Open Medical Journal
%D 2012
%I Limited liability company ?Science and Innovations? (Saratov)
%X Seasonality of thrombogenic disorders in coronary atherosclerosis recrudescence has been studied using a comparison of blood clotting peculiarities in patients with stable (n=167) and unstable angina (n=210) in different season periods. It was established that there is no common mechanism for decompensation of hemostasis system in progressive angina. The structure of thrombogenic disorders is non-homogeneous. In winter the most important thing is an activating of prothrombinase producing, and in spring ¨C reducing of heparin content and fibrinolysis activity inhibition. In summer thrombogenic changes are characterized by activating of intrinsic prothrombinase producing mechanism, antithrombin-III decreased activity and heparin content, fibrinolysis activity inhibition. In autumn an advanced euglobulin fibrinolysis block is enough to break the adaptation of hemostasis system.
%K atherosclerosis
%K angina
%K blood clotting
%K fibrinolysis
%K season disorders
%U http://www.romj.org/node/40