%0 Journal Article
%T The change in function of Th1 and Th2-lymphocytes and cytokine profile at chronic intoxication of ethanol
%A Andrey A. Svistunov
%A Pavel F. Zabrodskii
%A V.G. Lim and V.F.Grichin
%J Russian Open Medical Journal
%D 2012
%I Limited liability company ?Science and Innovations? (Saratov)
%X In experiments in non-inbred rats, it has been established that chronic intoxication of ethanol (30 days, total dose ¨C 6.0 LD50) essentially reduces concentration of cytokines IFN¦Ã, IL-2, IL-4, IL-10 in blood, increases concentration of IL-6, reduces an interrelation IFN¦Ã/IL-4 in comparison with the control, suppresses of immune responses, which displays the greater lesion of Th1-cells in comparison with Th2-lymphosytes.
%K ethanol
%K immunotoxity
%K cytokines
%K §´h1
%K Th2
%K lymphosytes
%U http://www.romj.org/node/30