%0 Journal Article
%T Oropharyngeal and oesophageal candidiasis in HIV infected patients.
%A Poonam Chanderlal Sharma
%J Asian Journal of Biomedical and Pharmaceutical Sciences
%D 2013
%I 
%X Background- Candidiasis is a common infection caused by yeast-like fungus. Oropharyngeal candidiasis occurs when CD4 count is 200-500 cell/mm3, with fall in CD4 count to <200 cells/mm3 oesophageal candidiasis occur in HIV infected patients.Aim- To identify and characterize Candida species (oropharyngeal and oesophageal) in HIV infected patients and to correlate them with CD4+ T lymphocyte count.Method- Two hundred HIV positive cases were selected for this study. Identification of Candida species was done by conventional standard techniques using Gram¡¯s stain, cultural character on Saboraud dextrose agar, germ tube test, morphology on corn meal agar, colour difference on CHROM agar and sugar assimilation test.Findings- The prevalence of candidiasis was 72.5% with majority of the patients belonged to age group 16 - 45 years. Male to female ratio was 1.64:1 with male preponderance. 58.62% of patients belonged to Stage 4 of WHO clinical staging. Majority of species (60.67%) were C. albicans. The non-Candida albicans isolated were C. dublinienses (25.33%), C. krusei (12.00%), C. tropicalis (1.33%) and C. glabrata (0.67%).Conclusion- Though Candida albicans continues to be the common and important pathogen among the Candida species there is a increase in the incidence of non- Candida albicans species like Candida dublinienses, Candida krusei, Candida tropicalis and Candida glabrata.
%U http://www.jbiopharm.com/index.php/ajbps/article/view/163