%0 Journal Article
%T Kaposi¡äs sarcoma following immunosuppressive therapy for vasculitis
%A Bouattar Tarik
%A Kazmouhi Laila
%A Alhamany Zaitouna
%A Beqqal Kawtar
%J Saudi Journal of Kidney Diseases and Transplantation
%D 2011
%I Medknow Publications
%X Kaposi¡äs sarcoma (KS) is widely reported to develop after renal transplantation and is induced by activation of a latent human herpes virus 8. We report the clinical features and outcome of a 50-year-old woman who presented with KS 18 weeks after starting immuno-suppressive therapy for vasculitis. She had positive-titer IgG antibody to human herpes virus 8. Cyclophosphamide pulses were interrupted, and prednisone was decreased gradually to 10 mg/day. Skin lesions showed important regression with stabilization of the general state and renal function. Eight months later, the patient presented with a diffuse cutaneous KS that required the discontinuation of steroids. Within 1 month, her general status and renal function deteriorated, and she died with a disseminated intravascular coagulation syndrome.
%U http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=2;spage=319;epage=323;aulast=Bouattar