%0 Journal Article
%T Prevalence of ToRCH agents in indigenous women in childbearing age, Zulia state, Venezuela Prevalencia de agentes ToRCH en mujeres ind赤genas en edad f谷rtil, estado Zulia, Venezuela
%A Francisca Mercedes Monsalve-C
%A Luciana Ana Costa-Le車n
%A Mar赤a Elena Castellano
%A Anais Su芍rez
%J Biom谷dica
%D 2012
%I Instituto Nacional de Salud
%X Introduction. ToRCH syndrome includes the following pathogens: Toxoplasma gondii, rubella, cytomegalovirus and herpes simplex virus 1 and 2. In susceptible pregnant women these pathogens can cause abortions and congenital malformation in the newborn babies. Objective. To determine the seroprevalence of infection by ToRCH agents in women of childbearing age in some Yukpa indigenous communities in Venezuela. Material and methods. During 2007, 109 samples were selected from a total of 151 women with an age range of 14 to 40 years old. The determination of antibodies against TORCH agents was carried out through the indirect enzyme immunoassay technique by ELISA＊s technique of Smartest Diagnostics. Results. 85.5%of the collected samples presented antibodies against T gondii, 95.4% for rubella, 75.2% for cytomegalovirus and 97.2% for and herpes simplex virus 1 and 2. 21.1% and 30.2% of women presented a relationship between abortion and infection by cytomegalovirus and herpes simplex virus 1and 2, respectively. Conclusions. The findings show a high prevalence of ToRCH agents in women in childbearing age in Yukpa indigenous communities in Venezuela. Poor sanitary conditions and consumption of water contaminated with oocysts may be an important way of transmission of T. gondii. Overcrowding in the communities, sexual activity at an early age and number of partners and may be related to the presence of cytomegalovirus and herpes simplex virus HSV-1 and 2. Introducci車n. El termino ToRCH comprende a los pat車genos: Toxoplasma gondii, rub谷ola, citomegalovirus y virus herpes simple 1 y 2. En embarazadas susceptibles pueden ser causas de abortos y malformaciones cong谷nitas en el neonato. Objetivo. Determinar la seroprevalencia de infecci車n por los agentes causantes del s赤ndrome ToRCH en mujeres en edad f谷rtil de algunas comunidades ind赤genas Yukpa de Venezuela. Materiales y m谷todos. En el a o 2007 fueron seleccionadas 109 muestras de un total de 151 mujeres en edades comprendidas entre 14 y 40 a os. La detecci車n de anticuerpos se realiz車 por el m谷todo de inmunoensayo enzim芍tico indirecto o ELISA de Smartest Diagnostics. Resultados. El 85,5% present車 anticuerpos contra T. gondii, el 95,4% para rub谷ola, el 75,2% para citomegalovirus y el 97,2 para el virus herpes simple 1 y 2. Se observa que el 21,1% y el 30,2% present車 relaci車n entre la variable aborto y las infecciones por citomegalovirus y virus herpes simple 1 y 2, respectivamente. Conclusiones. Existe alta seroprevalencia de infecciones por los agentes causantes del s赤ndrome ToRCH en mujeres en edad f谷rtil de la et
%U http://www.revistabiomedica.org/index.php/biomedica/article/view/749