%0 Journal Article
%T Identification of ¦Á-Glucosidase Inhibitors From Psidium guajava Leaves and Syzygium cumini Linn. Seeds
%A Kathirvel Alagesan
%A Prabhakar Thennarasu
%A Vinoth Kumar
%A Sadasivam Sankarnarayanan
%J International Journal of Pharma Sciences and Research
%D 2012
%I KEJA Publications
%X We screened for ¦Á-glucosidase inhibitors from 12 traditional medicinal plants used for the treatment of diabetes. Potent ¦Á-glucosidase inhibitory activity was found in aqueous extract of Psidium guajava leaves and Syzygium cumini Linn seed extract. Active principles inhibiting ¦Á-glucosidase were isolated and identified as apigenin 7- O-glucoside in the S.cumini Linn seed extract and Dihydro-3,3¡¯,4¡¯,5,7 ¨C pentahydroxyflavone glycoside in P.guajava leaf extract through FT-IR and LC-MS. The inhibitor present in both P.guajava leaves and S.cumini Linn seed extract was found to be reversible in nature.
%K Diabetes
%K ¦Á-glucosidase
%K Medicinal plants
%K P.guajava
%K Reversible inhibitor
%K S.cumini
%U http://www.ijpsr.info/docs/IJPSR12-03-02-009.pdf